Just watched a few of the high definition videos for this game from Crytek. It really is looking top notch. The studio is putting some real work into this one to utilize hardware that isn't even available yet.
It supports windows Vista, direct x10 and multi threading. So for the best experience your gonna need all the bells. It isn't shipping till Vista and direct x10 cards are available so most likely next year at a guess.
This looks like it will be one of the true next gen games.
Watch the videos and decide
http://www.gametrailers.com/gamepage.php?id=2509